Stochastic Optical Reconstruction Microscopy
— One of a family of optical microscopy techniques capable of overcoming the diffraction limit normally associated with optical microscopes.
permits optical microscopy to produce resolutions that can discern individual molecules in living tissue.
The diffraction limit, which STORM overcomes, is not based on the quality of a microscope's optics, but by a physical property related to the wavelength of light. For this reason, optical microscopy was long thought to be incapable of ever being able to resolve features smaller than about 250 nanometers.